Pub. Date : 1997 Mar
PMID : 9067893
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ET-1-induced activation of JNK was blocked by BQ-123, an antagonist for the ETA receptor. | cyclo(Trp-Asp-Pro-Val-Leu) | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA). | Calcium | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA). | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | In contrast, ET-1-induced activation of JNK was significantly reduced by calcium chelation (with BAPTA/AM and EGTA). | Egtazic Acid | mitogen-activated protein kinase 8 | Homo sapiens |
| 5 | In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK. | Ionomycin | mitogen-activated protein kinase 8 | Homo sapiens |
| 6 | In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK. | Calcium | mitogen-activated protein kinase 8 | Homo sapiens |
| 7 | In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK. | Thapsigargin | mitogen-activated protein kinase 8 | Homo sapiens |
| 8 | In addition, ionomycin, a calcium ionophore, and thapsigargin, an intracellular calcium-rising agent, were able to induce the activation of JNK. | Calcium | mitogen-activated protein kinase 8 | Homo sapiens |
| 9 | ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein). | herbimycin | mitogen-activated protein kinase 8 | Homo sapiens |
| 10 | ET-1-induced activation of JNK was also inhibited by PTK inhibitors (herbimycin A and genistein). | Genistein | mitogen-activated protein kinase 8 | Homo sapiens |
| 11 | These results indicate that ET-1 is able to activate JNK in glomerular mesangial cells through PKC-independent and PTK-dependent pathways and intracellular calcium is necessary to the activation of JNK. | Calcium | mitogen-activated protein kinase 8 | Homo sapiens |