Title : Design and modeling of new platelet-activating factor antagonists. 2. Synthesis and biological activity of 1,4-bis-(3',4',5'-trimethoxybenzoyl)-2-alkyl and 2-alkyloxymethylpiperazines.

Pub. Date : 1997 Jan

PMID : 9034961






1 Functional Relationships(s)
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1 In the continuation of our investigations on the structure of platelet-activating factor (PAF)-receptor, 25 additional 2-substituted 1,4-bis-(poly- and mono methoxybenzoyl)-piperazines were synthesized and their in vitro biological activities measured. 2-substituted 1,4-bis-(poly- and mono methoxybenzoyl)-piperazines platelet activating factor receptor Homo sapiens