Pub. Date : 1996 Dec
PMID : 8989915
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. | Urethane | transformation related protein 53, pseudogene | Mus musculus |
| 2 | To test this hypothesis, we investigated the presence of mutations involving Ki-ras and p53 in urethane-induced lung lesions in A/J mice at early and late stages of tumorigenesis. | Urethane | transformation related protein 53, pseudogene | Mus musculus |
| 3 | These results indicate that Ki-ras mutations arise early, whereas p53 mutations occur relatively late during the benign stages of urethane-induced lung carcinogenesis in A/J mice. | Urethane | transformation related protein 53, pseudogene | Mus musculus |