Pub. Date : 1996 Dec
PMID : 8967975
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 2 | Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance. | Camptothecin | transformation related protein 53, pseudogene | Mus musculus |
| 3 | Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance. | Paclitaxel | transformation related protein 53, pseudogene | Mus musculus |
| 4 | However, these mutant p53-transfected cell lines retained sensitivity to taxol and camptothecin. | Paclitaxel | transformation related protein 53, pseudogene | Mus musculus |
| 5 | However, these mutant p53-transfected cell lines retained sensitivity to taxol and camptothecin. | Camptothecin | transformation related protein 53, pseudogene | Mus musculus |
| 6 | We also show that immature thymocytes from mice with the p53 gene genetically inactivated showed reduced ability to undergo apoptosis after treatment with ionizing radiation and cisplatin compared with wild-type mice. | Cisplatin | transformation related protein 53, pseudogene | Mus musculus |
| 7 | Camptothecin also induced apoptosis in a p53-independent manner in thymocytes at low doses but in a p53-dependent manner at high doses. | Camptothecin | transformation related protein 53, pseudogene | Mus musculus |
| 8 | Camptothecin also induced apoptosis in a p53-independent manner in thymocytes at low doses but in a p53-dependent manner at high doses. | Camptothecin | transformation related protein 53, pseudogene | Mus musculus |
| 9 | These data suggest that taxoids and camptothecin analogs could have activity in tumors that have aberrant p53 function and provide a rationale for the clinical observations of responsiveness of refractory ovarian cancer to these drugs. | Taxoids | transformation related protein 53, pseudogene | Mus musculus |
| 10 | These data suggest that taxoids and camptothecin analogs could have activity in tumors that have aberrant p53 function and provide a rationale for the clinical observations of responsiveness of refractory ovarian cancer to these drugs. | Camptothecin | transformation related protein 53, pseudogene | Mus musculus |