Pub. Date : 1996 Nov 15
PMID : 8910602
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mutation of phosphoserine 389 affects p53 function in vivo. | Phosphoserine | transformation related protein 53, pseudogene | Mus musculus |
| 2 | Mutations of murine p53 serine residues individually to either alanine or glutamic acid at positions 7, 9, 12, 18, 37, 312, and 389 resulted in equivalent levels of transcriptional activation in standard transient transfection experiments. | Serine | transformation related protein 53, pseudogene | Mus musculus |
| 3 | We also demonstrated that specific phosphorylation of p53 at serine 389 is induced by cyclin E overexpression in high-density cells. | Serine | transformation related protein 53, pseudogene | Mus musculus |
| 4 | Our data establish for the first time that phosphorylation of p53 at serine 389 is important in activating its function in vivo. | Serine | transformation related protein 53, pseudogene | Mus musculus |