Pub. Date : 1996 Nov 1
PMID : 8910292
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This prompted us to explore the possibility that kinases other than Pak might participate in signaling from GTP-binding proteins to JNK. | Guanosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Furthermore, we present evidence that MLK3 binds the GTP-binding proteins Cdc42 and Rac1 in vivo and that MLK3 mediates activation of MEKK-SEK-JNK kinase cascade by Rac1 and Cdc42. | Guanosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |
3 | Taken together, these findings strongly suggest that members of the novel MLK family of highly related kinases link small GTP-binding proteins to the JNK signaling pathway. | Guanosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |