Title : The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase.

Pub. Date : 1996 Oct 25

PMID : 8900190






2 Functional Relationships(s)
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1 The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase. Ro 31-8220 mitogen-activated protein kinase 8 Homo sapiens
2 Furthermore, Ro-31-8220 apparently activates JNK in a PKC-independent manner. ro-31 mitogen-activated protein kinase 8 Homo sapiens