Title : Slow rate of phosphodiester bond formation accounts for the strong bias that Taq DNA polymerase shows against 2',3'-dideoxynucleotide terminators.

Pub. Date : 1996 Feb 20

PMID : 8652560






1 Functional Relationships(s)
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Protein Name
Organism
1 In steady-state experiments, Taq Pol I was strongly biased in favor of dATP1 over ddATP incorporation by about 700 to 1, in contrast to T7 DNA polymerase which showed a preference of only about 4 to 1. 2',3'-dideoxyadenosine triphosphate DNA polymerase iota Homo sapiens