Pub. Date : 1993 Aug 15
PMID : 8394344
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transcriptional modulation of platelet-activating factor receptor gene expression by cyclic AMP. | Cyclic AMP | platelet activating factor receptor | Homo sapiens |
| 2 | We examined the effects of increasing intracellular cyclic AMP levels on the expression of human PAF receptor (hPAF-R). | Cyclic AMP | platelet activating factor receptor | Homo sapiens |
| 3 | A transiently elevated intracellular concentration of AMP induced with prostaglandin E2, cholera toxin, or forskolin was a sufficient signal to inhibit PAF-R expression. | Adenosine Monophosphate | platelet activating factor receptor | Homo sapiens |
| 4 | A transiently elevated intracellular concentration of AMP induced with prostaglandin E2, cholera toxin, or forskolin was a sufficient signal to inhibit PAF-R expression. | Dinoprostone | platelet activating factor receptor | Homo sapiens |
| 5 | A transiently elevated intracellular concentration of AMP induced with prostaglandin E2, cholera toxin, or forskolin was a sufficient signal to inhibit PAF-R expression. | Colforsin | platelet activating factor receptor | Homo sapiens |
| 6 | cAMP reduced the expression of hPAF-R in a concentration- and a time-dependent manner. | Cyclic AMP | platelet activating factor receptor | Homo sapiens |
| 7 | Moreover, the nuclear transcription rate of the hPAF-R gene was reduced as early as 30 min after stimulation with cAMP. | Cyclic AMP | platelet activating factor receptor | Homo sapiens |
| 8 | These data indicate that PAF-R expression can be regulated at the transcriptional and possibly post-transcriptional levels by elevation of intracellular cAMP. | Cyclic AMP | platelet activating factor receptor | Homo sapiens |