Pub. Date : 1976 Jul
PMID : 820546
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In hypothalamic and cortical tissue preparations, on incubation with TRH labeled with [3H]proline, fast formation of radioactively labeled deamido-TRH and liberation of prolineamide and free proline were found. | Proline | thyrotropin releasing hormone | Homo sapiens |
| 2 | The peptidolytic cleavage of TRH by brain enzymes, yielding proline and prolineamide as split products, was also effectively reduced using comparatively high concentrations of the dipeptide ester without, however, preventing TRH deamidation. | Proline | thyrotropin releasing hormone | Homo sapiens |
| 3 | Using [14C]proline as the label, it appeared that rather large amounts of radioactively labeled deamido-TRH, which was identified as such by vigorous purification, could be isolated from such incubates. | Proline | thyrotropin releasing hormone | Homo sapiens |