Title : Natural cytotoxicity in breast cancer patients receiving neoadjuvant chemotherapy: effects of L-arginine supplementation.

Pub. Date : 1994 Aug

PMID : 8076711






3 Functional Relationships(s)
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1 In this study, the effect of L-arginine supplementation on natural cytotoxicity was determined in patients with breast cancer receiving CHOP chemotherapy. Arginine DNA damage inducible transcript 3 Homo sapiens
2 Those patients receiving L-arginine supplementation (30 g/day for 3 days prior to each course of chemotherapy) had a smaller and delayed onset of immunosuppression (day 14), compared with those patients who had CHOP only (day 9). Arginine DNA damage inducible transcript 3 Homo sapiens
3 L-Arginine was able to repeatedly stimulate NK and LAK cell cytotoxicity in patients who were receiving CHOP chemotherapy (P < 0.003). Arginine DNA damage inducible transcript 3 Homo sapiens