Pub. Date : 1994 Mar
PMID : 8015384
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BBH induced a significant increase in the abundance of both GLUT1 and actin mRNAs, and this effect was dose and time dependent. | alpha-hexachlorocyclohexane | solute carrier family 2 member 1 | Bos taurus |
| 2 | BBH induced a significant increase in the abundance of both GLUT1 and actin mRNAs, and this effect was dose and time dependent. | alpha-hexachlorocyclohexane | actin epsilon 1 | Bos taurus |
| 3 | To determine whether known growth factors cause BBH-like induction of GLUT1 and actin mRNAs, a series of growth factors was also tested. | alpha-hexachlorocyclohexane | solute carrier family 2 member 1 | Bos taurus |
| 4 | To determine whether known growth factors cause BBH-like induction of GLUT1 and actin mRNAs, a series of growth factors was also tested. | alpha-hexachlorocyclohexane | actin epsilon 1 | Bos taurus |
| 5 | Basic FGF had a moderate effect and TNF alpha partially mimicked the effect of BBH on both GLUT1 and actin transcripts. | alpha-hexachlorocyclohexane | tumor necrosis factor | Bos taurus |
| 6 | Basic FGF had a moderate effect and TNF alpha partially mimicked the effect of BBH on both GLUT1 and actin transcripts. | alpha-hexachlorocyclohexane | solute carrier family 2 member 1 | Bos taurus |
| 7 | Basic FGF had a moderate effect and TNF alpha partially mimicked the effect of BBH on both GLUT1 and actin transcripts. | alpha-hexachlorocyclohexane | actin epsilon 1 | Bos taurus |
| 8 | The present data suggests that brain-derived trophic factors present in BBH stimulate BBB-GLUT1 glucose transporter gene expression in ECL cells through a transcriptional mechanism. | alpha-hexachlorocyclohexane | solute carrier family 2 member 1 | Bos taurus |
| 9 | Therefore, BBH may be a useful model to study the characterization of soluble brain-derived trophic factors involved in the induction of BBB-GLUT1 gene expression. | alpha-hexachlorocyclohexane | solute carrier family 2 member 1 | Bos taurus |