Title : Protein kinase C modulation of rhodanese-catalyzed conversion of cyanide to thiocyanate.

Pub. Date : 1994 Nov

PMID : 7881866






4 Functional Relationships(s)
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1 We examined HI-6"s effect on rhodanese-catalyzed SCN- production. asoxime chloride thiosulfate sulfurtransferase Bos taurus
2 With HI-6 at 1 or 10 microM used in place of PKC, or TPA, rhodanese activity was increased by 6 or 14% (P < 0.05), respectively, compared to control. asoxime chloride thiosulfate sulfurtransferase Bos taurus
3 Under the conditions examined, exogenous PKC acting as a possible phosphate acceptor, and HI-6, a potential dephosphorylating compound, increased rhodanese activity. asoxime chloride thiosulfate sulfurtransferase Bos taurus
4 It is suggested that addition of purified, exogenous PKC may accept phosphate from phosphorylated rhodanese or HI-6 may dephosphorylate rhodanese, both of which stimulate the conversion of cyanide anion to the less toxic SCN-. asoxime chloride thiosulfate sulfurtransferase Bos taurus