Title : A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice.

Pub. Date : 1995 Mar

PMID : 7773294






3 Functional Relationships(s)
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1 Thus, the mutant Val-135 p53 allele may act in vivo in a dominant negative manner in the presence of wild-type p53 but does not display gain of function activity in the absence of wild-type p53. Valine transformation related protein 53, pseudogene Mus musculus
2 Thus, the mutant Val-135 p53 allele may act in vivo in a dominant negative manner in the presence of wild-type p53 but does not display gain of function activity in the absence of wild-type p53. Valine transformation related protein 53, pseudogene Mus musculus
3 Thus, the mutant Val-135 p53 allele may act in vivo in a dominant negative manner in the presence of wild-type p53 but does not display gain of function activity in the absence of wild-type p53. Valine transformation related protein 53, pseudogene Mus musculus