Title : Modulation of O6-methylguanine-DNA methyltransferase-mediated nimustine resistance in recurrent malignant gliomas by streptozotocin--a preliminary report.

Pub. Date : 1995 Mar-Apr

PMID : 7763050






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Modulation of O6-methylguanine-DNA methyltransferase-mediated nimustine resistance in recurrent malignant gliomas by streptozotocin--a preliminary report. Nimustine O-6-methylguanine-DNA methyltransferase Homo sapiens
2 This trial is based on the strategy of reversing O6-methylguanine-DNA methyltransferase (MGMT)-mediated nimustine resistance by depleting MGMT activity with streptozotocin (STZ) pretreatment. Nimustine O-6-methylguanine-DNA methyltransferase Homo sapiens
3 This trial is based on the strategy of reversing O6-methylguanine-DNA methyltransferase (MGMT)-mediated nimustine resistance by depleting MGMT activity with streptozotocin (STZ) pretreatment. Nimustine O-6-methylguanine-DNA methyltransferase Homo sapiens
4 The preliminary results indicated that nimustine-resistant tumor cells in vivo could also be sensitized by modulation of MGMT activity. Nimustine O-6-methylguanine-DNA methyltransferase Homo sapiens