Title : Cell death due to ACNU-induced DNA fragmentation: inhibition by cycloheximide.

Pub. Date : 1994

PMID : 7714548






2 Functional Relationships(s)
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1 Exposure of rat glioma cell line KEG-1 to ACNU for 2 hours resulted in oligonucleosomal DNA fragmentation, creating a "ladder" on agarose gel electrophoresis. Nimustine glycine-N-acyltransferase-like 2 Rattus norvegicus
2 Cycloheximide-inhibitable DNA fragmentation was also found in the KEG-1 implanted in vivo rat model following the administration of ACNU. Nimustine glycine-N-acyltransferase-like 2 Rattus norvegicus