Title : Coagulation factor Va is an actin filament binding and cross-linking protein.

Pub. Date : 1995 Jan-Feb

PMID : 7662308






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Bovine coagulation cofactor factor Va is shown to bind to filament of skeletal muscle actin with a dissociation constant of 40-50 nM in the presence of 50 mM NaCl. Sodium Chloride actin epsilon 1 Bos taurus
2 The binding of factor Va to F-actin was inhibited by increasing ionic strength, being approximately 20-fold weaker at 150 mM NaCl. Sodium Chloride actin epsilon 1 Bos taurus
3 Actin filaments had only a slight inhibitory effect on the prothombinase activity of the factor Va-factor Xa-phospholipid complex. Phospholipids actin epsilon 1 Bos taurus