Title : The Grb2 adaptor.

Pub. Date : 1995 Aug 1

PMID : 7641883






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Binding of the Grb2 SH2 domain to phosphotyrosine motifs on receptors, or other adaptor proteins such as Shc, recruits this Grb2/Sos complex at the plasma membrane where Sos stimulates nucleotide exchange on ras, then ras activates raf and leads to MAP kinase activation. Phosphotyrosine growth factor receptor bound protein 2 Homo sapiens
2 Binding of the Grb2 SH2 domain to phosphotyrosine motifs on receptors, or other adaptor proteins such as Shc, recruits this Grb2/Sos complex at the plasma membrane where Sos stimulates nucleotide exchange on ras, then ras activates raf and leads to MAP kinase activation. Phosphotyrosine growth factor receptor bound protein 2 Homo sapiens
3 Binding of the Grb2 SH2 domain to phosphotyrosine motifs on receptors, or other adaptor proteins such as Shc, recruits this Grb2/Sos complex at the plasma membrane where Sos stimulates nucleotide exchange on ras, then ras activates raf and leads to MAP kinase activation. sulfur monoxide growth factor receptor bound protein 2 Homo sapiens
4 Binding of the Grb2 SH2 domain to phosphotyrosine motifs on receptors, or other adaptor proteins such as Shc, recruits this Grb2/Sos complex at the plasma membrane where Sos stimulates nucleotide exchange on ras, then ras activates raf and leads to MAP kinase activation. sulfur monoxide growth factor receptor bound protein 2 Homo sapiens