Title : Mast cells lacking the high affinity immunoglobulin E receptor are deficient in Fc epsilon RI gamma messenger RNA.

Pub. Date : 1995 Aug 1

PMID : 7629513






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ionomycin, but not IgE immune complexes, causes these cells to release serotonin and to express IL-3 and IL-13 mRNA, consistent with their being FC epsilon RI-deficient mast cells. Ionomycin Fc epsilon receptor Ia Homo sapiens
2 These stable transfectants released serotonin in response to cross-linkage of Fc epsilon RI, demonstrating that the molecular defect of p161+/Fc epsilon RI- mast cells is indeed the loss of Fc epsilon RI gamma expression. Serotonin Fc epsilon receptor Ia Homo sapiens