Pub. Date : 1995 Jul 28
PMID : 7629120
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | c-Jun N-terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes. | Cyclic AMP | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | In contrast, another MAP kinase homologue c-Jun N-terminal kinase (JNK) was inhibited by cAMP in good correlation with that of IL-2 suppression. | Cyclic AMP | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | In contrast, another MAP kinase homologue c-Jun N-terminal kinase (JNK) was inhibited by cAMP in good correlation with that of IL-2 suppression. | Cyclic AMP | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | Moreover, JNK was antagonized by a delayed kinetics which is characteristic of cAMP inhibition. | Cyclic AMP | mitogen-activated protein kinase 8 | Homo sapiens |
| 5 | Despite that both ERK and JNK are essential for T cell activation, selective inhibition by cAMP further supports the specific role of JNK in T cell activation. | Cyclic AMP | mitogen-activated protein kinase 8 | Homo sapiens |