Pub. Date : 1995 Jul 17
PMID : 7628439
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reconstitution of the complete tetrameric Fc epsilon RI receptor, lyn and syk in a non-hematopoietic "null" cell line is sufficient to reconstruct clustering-controlled receptor tyrosine phosphorylation and activation of syk, without apparent requirement for hematopoietic specific phosphatases. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 2 | Lyn also participates in the tyrosine phosphorylation and activation of syk in a manner which is dependent on phosphorylated Fc epsilon RI. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 3 | Based on these results, we propose that receptor clustering controls lyn-mediated Fc epsilon RI tyrosine phosphorylation by shifting a balance between phosphorylation and dephosphorylation towards accumulation of tyrosine phosphorylated Fc epsilon RI. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 4 | Based on these results, we propose that receptor clustering controls lyn-mediated Fc epsilon RI tyrosine phosphorylation by shifting a balance between phosphorylation and dephosphorylation towards accumulation of tyrosine phosphorylated Fc epsilon RI. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 5 | Based on these results, we propose that receptor clustering controls lyn-mediated Fc epsilon RI tyrosine phosphorylation by shifting a balance between phosphorylation and dephosphorylation towards accumulation of tyrosine phosphorylated Fc epsilon RI. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 6 | Based on these results, we propose that receptor clustering controls lyn-mediated Fc epsilon RI tyrosine phosphorylation by shifting a balance between phosphorylation and dephosphorylation towards accumulation of tyrosine phosphorylated Fc epsilon RI. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 7 | Fc epsilon RI tyrosine phosphorylation functions to bring syk into a microenvironment where it becomes tyrosine phosphorylated and activated, thereby allowing clustering to indirectly control syk activity. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |
| 8 | Fc epsilon RI tyrosine phosphorylation functions to bring syk into a microenvironment where it becomes tyrosine phosphorylated and activated, thereby allowing clustering to indirectly control syk activity. | Tyrosine | Fc epsilon receptor Ia | Homo sapiens |