Pub. Date : 1995 Aug
PMID : 7564103
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human mesangial cell production of monocyte chemoattractant protein-1: modulation by lovastatin. | Lovastatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by lovastatin resulted in a reduction of the mesangial cell-derived chemotactic activity as well as MCP-1 mRNA expression. | Lovastatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | The inhibitory effects of lovastatin in the presence of exogenous cholesterol were reversed by mevalonate, suggesting a role for isoprenoid intermediates of the mevalonate pathway and/or isoprenylated proteins in mesangial cell MCP-1 regulation. | Lovastatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | The inhibitory effects of lovastatin in the presence of exogenous cholesterol were reversed by mevalonate, suggesting a role for isoprenoid intermediates of the mevalonate pathway and/or isoprenylated proteins in mesangial cell MCP-1 regulation. | Mevalonic Acid | C-C motif chemokine ligand 2 | Homo sapiens |