Title : Stereochemistry and mechanism of reactions catalyzed by indolyl-3-alkane alpha-hydroxylase.

Pub. Date : 1979 Jul 25

PMID : 447726






3 Functional Relationships(s)
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Protein Name
Organism
1 The reaction of tryptamine with indolyl-3-alkane alpha-hydroxylase is shown to remove stereospecifically the pro-S hydrogen at C-2 of the side chain and to give hydroxytryptamine of "R" configuration. Proline complement C2 Homo sapiens
2 In the reaction of L-tryptophan methyl ester, the enzyme also catalyzes stereospecific removal of the pro-S hydrogen at C-3, but the product 3-hydroxytryptophan methyl ester is racemic at C-3. Proline complement C3 Homo sapiens
3 In the reaction of L-tryptophan methyl ester, the enzyme also catalyzes stereospecific removal of the pro-S hydrogen at C-3, but the product 3-hydroxytryptophan methyl ester is racemic at C-3. Proline complement C3 Homo sapiens