Title : Up-regulation of Nrf2/HO-1 and inhibition of TGF-β1/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice.

Pub. Date : 2022 Jun

PMID : 35513128






2 Functional Relationships(s)
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1 Up-regulation of Nrf2/HO-1 and inhibition of TGF-beta1/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice. daphnetin transforming growth factor, beta 1 Mus musculus
2 Taken together, Daph effectively counteracted the TAC-induced cardiac hypertrophy and fibrosis by improving the Nrf2/HO-1 axis and inhibiting the TGF-beta1/Smad2/3 signaling axis. daphnetin transforming growth factor, beta 1 Mus musculus