Title : Airway epithelial Paraoxonase-2 in obese asthma.

Pub. Date : 2022

PMID : 35286330






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 with 25muM quercetin significantly increased PON2 protein levels: 15.5 treated cells vs. 9.8 untreated cells (relative units normalized by GAPDH) (p value = 0.004). Quercetin paraoxonase 2 Homo sapiens
2 Notably, compared to untreated cells, quercetin supplementation reduces mitochondrial superoxide and hydrogen peroxide production on HBECs cells exposed to different oxidative stress triggers such as 1-2 Naphthoquinone (1-2 NQ) and hydrogen peroxide, suggesting that PON2 might play a protective role ameliorating oxidative injury on human airway epithelium. Quercetin paraoxonase 2 Homo sapiens
3 Treatment with quercetin in vitro increased PON2 protein levels and prevented oxidative stress from different types of stimuli. Quercetin paraoxonase 2 Homo sapiens