Title : Cholesterol crystals activate NLRP3 inflammasomes and promote gallstone formation by increasing mucin secretion.

Pub. Date : 2022 Mar 1

PMID : 35227133






2 Functional Relationships(s)
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1 Also, the IL-1 receptor antagonist, IL1RA, and caspase-1 inhibitor, Ac-YVAD, both inhibited MUC5AC secretion induced by cholesterol crystals. Cholesterol interleukin 1 receptor antagonist Homo sapiens
2 Also, the IL-1 receptor antagonist, IL1RA, and caspase-1 inhibitor, Ac-YVAD, both inhibited MUC5AC secretion induced by cholesterol crystals. Cholesterol interleukin 1 receptor antagonist Homo sapiens