Pub. Date : 2021
PMID : 34714861
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A significant difference in enzyme activity of the catalytic site mutants was observed as compared to the wildtype, and subsequent AChE activity showed that esterase activity of PON2 is responsible for the hydrolysis of DHC and PB. | Donepezil | paraoxonase 2 | Homo sapiens |
| 2 | A significant difference in enzyme activity of the catalytic site mutants was observed as compared to the wildtype, and subsequent AChE activity showed that esterase activity of PON2 is responsible for the hydrolysis of DHC and PB. | Pyridostigmine Bromide | paraoxonase 2 | Homo sapiens |
| 3 | Thus, our data suggested that the esterase activity of PON2 was mainly responsible for the hydrolysis of AChEI, DHC, and PB, and that might be responsible for the variation in individual response to AChEI therapy. | Donepezil | paraoxonase 2 | Homo sapiens |
| 4 | Thus, our data suggested that the esterase activity of PON2 was mainly responsible for the hydrolysis of AChEI, DHC, and PB, and that might be responsible for the variation in individual response to AChEI therapy. | Pyridostigmine Bromide | paraoxonase 2 | Homo sapiens |