Title : Regio- and stereochemical studies on the alpha-carbon oxidation of (S)-nicotine by cytochrome P-450 model systems.

Pub. Date : 1988 Mar

PMID : 3346880






2 Functional Relationships(s)
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1 Results from previous studies indicate that rabbit liver microsomal cytochrome P-450 catalyzes the C-5" two-electron oxidation of (S)-nicotine stereoselectivity with preferential loss of the pro-(E)-hydrogen atom trans to the pyridine ring. pyridine cytochrome P-450 Oryctolagus cuniculus
2 Results from previous studies indicate that rabbit liver microsomal cytochrome P-450 catalyzes the C-5" two-electron oxidation of (S)-nicotine stereoselectivity with preferential loss of the pro-(E)-hydrogen atom trans to the pyridine ring. pyridine complement C5 Oryctolagus cuniculus