Title : Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.

Pub. Date : 2020 Sep 21

PMID : 32759267






4 Functional Relationships(s)
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Protein Name
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1 The major protease (Mpro) of SARS-CoV-2 is considered a promising target, based on previous results from related CoVs with lopinavir (LPV), an HIV protease inhibitor. Lopinavir NEWENTRY Severe acute respiratory syndrome-related coronavirus
2 The major protease (Mpro) of SARS-CoV-2 is considered a promising target, based on previous results from related CoVs with lopinavir (LPV), an HIV protease inhibitor. Lopinavir NEWENTRY Severe acute respiratory syndrome-related coronavirus
3 Our results show that ATV could dock in the active site of SARS-CoV-2 Mpro, with greater strength than LPV, blocking Mpro activity. Lopinavir NEWENTRY Severe acute respiratory syndrome-related coronavirus
4 Our results show that ATV could dock in the active site of SARS-CoV-2 Mpro, with greater strength than LPV, blocking Mpro activity. Lopinavir NEWENTRY Severe acute respiratory syndrome-related coronavirus