Title : Inhibitory Effects of Indirubin-3'-oxime Derivatives on Lipid Accumulation in 3T3-L1 Cells.

Pub. Date : 2020

PMID : 32115509






2 Functional Relationships(s)
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1 Furthermore, 5-methoxyindirubin-3"-oxime (2) and 6-bromoindirubin-3"-oxime (7) markedly suppressed the expression of CCAAT/enhancer-binding protein alpha, peroxisome proliferator activator gamma2, and adipocyte protein 2, both of which are key adipogenic regulators at the intermediate stage of adipocyte differentiation. 5-methoxyindirubin 3'-oxime gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
2 Furthermore, 5-methoxyindirubin-3"-oxime (2) and 6-bromoindirubin-3"-oxime (7) markedly suppressed the expression of CCAAT/enhancer-binding protein alpha, peroxisome proliferator activator gamma2, and adipocyte protein 2, both of which are key adipogenic regulators at the intermediate stage of adipocyte differentiation. 6-bromoindirubin-3'-oxime gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus