Title : Prolinase activity in prolidase-deficient fibroblasts.

Pub. Date : 1988

PMID : 3148067






3 Functional Relationships(s)
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1 With pro-val as substrate and manganese in the reaction buffer, prolinase activity was higher in prolidase-deficient cells than in control cells (mean (SEM) 917 (67) nmol min-1 mg-1, n = 3, control mean (SEM) 294, (50), n = 11). prolylvaline peptidase D Homo sapiens
2 With pro-val as substrate and manganese in the reaction buffer, prolinase activity was higher in prolidase-deficient cells than in control cells (mean (SEM) 917 (67) nmol min-1 mg-1, n = 3, control mean (SEM) 294, (50), n = 11). Manganese peptidase D Homo sapiens
3 We suggest that in prolidase-deficient fibroblasts, this rise in prolinase activity constitutes an attempt to compensate for the prolidase deficiency by increasing the greatly reduced intracellular proline pool. Proline peptidase D Homo sapiens