Pub. Date : 2019 Nov
PMID : 31392364
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Siponimod pharmacokinetics, safety, and tolerability in combination with the potent CYP3A4 inhibitor itraconazole in healthy subjects with different CYP2C9 genotypes. | siponimod | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | Siponimod pharmacokinetics, safety, and tolerability in combination with the potent CYP3A4 inhibitor itraconazole in healthy subjects with different CYP2C9 genotypes. | siponimod | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | PURPOSE: To evaluate the PK and safety of siponimod, a substrate of CYP2C9/3A4, in the presence or absence of a CYP3A4 inhibitor, itraconazole. | siponimod | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |