Title : Paricalcitol attenuates TGF-β1-induced phenotype transition of human peritoneal mesothelial cells (HPMCs) via modulation of oxidative stress and NLRP3 inflammasome.

Pub. Date : 2019 Feb

PMID : 30354670






1 Functional Relationships(s)
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1 Paricalcitol alleviated TGF-beta1-induced EMT and the NLRP3 inflammasome, which was associated with a down-regulation of NOX activity by interfering with p47phox and p22phox interaction and mitochondrial NOX4 production in HPMCs. paricalcitol cytochrome b-245 alpha chain Homo sapiens