Title : Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.

Pub. Date : 2018

PMID : 29975924






1 Functional Relationships(s)
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1 Moreover, ALA treatment attenuated monocyte adhesion, suppressed cellular apoptosis, and eliminated excessive generation of intracellular reactive oxygen species (ROS) by reducing the protein levels of ROS-generating enzymes Nox4 and p22phox, as well as inhibiting NF-kappaB activation in HAECs stimulated by H2O2. Thioctic Acid cytochrome b-245 alpha chain Homo sapiens