Pub. Date : 2016 Feb
PMID : 26688241
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, the evaluation on the changes of metabolic enzymes revealed that HBCD and alpha-HCH shared a similar pattern of cytochrome P450 induction (CYP2B6), which was different from those of PCBs and BDE47 (CYP1A1 and CYP2B6). | alpha-hexachlorocyclohexane | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Moreover, the evaluation on the changes of metabolic enzymes revealed that HBCD and alpha-HCH shared a similar pattern of cytochrome P450 induction (CYP2B6), which was different from those of PCBs and BDE47 (CYP1A1 and CYP2B6). | alpha-hexachlorocyclohexane | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | These results indicated that low concentrations of HBCD could induce "adaptive responses" to the subsequent treatment with high concentrations of HBCD/alpha-HCH in L02 cells, which was associated with the PI3K/Akt pathway, and AMPK and p38 MAPK signaling. | alpha-hexachlorocyclohexane | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | These results indicated that low concentrations of HBCD could induce "adaptive responses" to the subsequent treatment with high concentrations of HBCD/alpha-HCH in L02 cells, which was associated with the PI3K/Akt pathway, and AMPK and p38 MAPK signaling. | alpha-hexachlorocyclohexane | mitogen-activated protein kinase 14 | Homo sapiens |