Title : Bromodomain-Containing Protein 4: The Epigenetic Origin of Pulmonary Arterial Hypertension.

Pub. Date : 2015 Aug 28

PMID : 26224795






3 Functional Relationships(s)
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1 METHODS AND RESULTS: BRD4 is upregulated in lungs, distal PAs, and PASMCs of patients with PAH compared with controls. Protactinium bromodomain containing 4 Homo sapiens
2 METHODS AND RESULTS: BRD4 is upregulated in lungs, distal PAs, and PASMCs of patients with PAH compared with controls. pasmcs bromodomain containing 4 Homo sapiens
3 We further studied the molecular downstream targets of BRD4 by inhibiting its activity in PAH-PASMCs using a clinically available inhibitor JQ1. pah-pasmcs bromodomain containing 4 Homo sapiens