Pub. Date : 2014 Dec 19
PMID : 25290579
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We test the sensitivity, accuracy, and speed of this method with small molecule ligands (+)-JQ1, BI2536, Dinaciclib, TG101348, and acetaminophen using three bromodomains Brd4, BrdT, and BPTF. | Fedratinib | bromodomain containing 4 | Homo sapiens |
| 2 | We test the sensitivity, accuracy, and speed of this method with small molecule ligands (+)-JQ1, BI2536, Dinaciclib, TG101348, and acetaminophen using three bromodomains Brd4, BrdT, and BPTF. | Acetaminophen | bromodomain containing 4 | Homo sapiens |
| 3 | Fluorine labeling only modestly affected the Brd4 structure and function assessed by isothermal titration calorimetry, circular dichroism, and X-ray crystallography. | Fluorine | bromodomain containing 4 | Homo sapiens |