Pub. Date : 2014 Oct
PMID : 25088707
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth. | N-[5-[[4-[[5-[[5-[[5-[[5-[[3-[3-(Dimethylamino)propylamino]-3-Oxidanylidene-Propyl]carbamoyl]-1-Methyl-Pyrrol-3-Yl]carbamoyl]-1-Methyl-Pyrrol-3-Yl]carbamoyl]-1-Methyl-Pyrrol-3-Yl]carbamoyl]-1-Methyl-Pyrrol-3-Yl]amino]-4-Oxidanylidene-Butyl]carbamoyl]-1-Methyl-Pyrrol-3-Yl]-1-Methyl-4-[[1-Methyl-4-[(1-Methylimidazol-2-Yl)carbonylamino]pyrrol-2-Yl]carbonylamino]imidazole-2-Carboxamide | transmembrane serine protease 2 | Homo sapiens |
| 2 | In the present study, we designed a PI polyamide targeting TMPRSS2-ERG translocation breakpoints and assessed its effect on human prostate cancer cells. | pi polyamide | transmembrane serine protease 2 | Homo sapiens |