Title : Fatty acid cyclooxygenase activity stimulated by transforming growth factor-beta in mouse osteoblastic cells (MC3T3-E1).

Pub. Date : 1989 May 1

PMID : 2495768






3 Functional Relationships(s)
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Protein Name
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1 The PGE2 synthesis started after a 1-h lag phase, and reached a maximum at about 3 h after the addition of TGF-beta. Dinoprostone transforming growth factor, beta 1 Mus musculus
2 The presence of TGF-beta enhanced the cyclooxygenase activity (arachidonic acid----PGH2) assayed with the microsomes or the immunoprecipitate from the solubilized enzyme. arachidonic acid----pgh2 transforming growth factor, beta 1 Mus musculus
3 The TGF-beta-stimulated PGE2 synthesis was blocked by translation and transcription inhibitors. Dinoprostone transforming growth factor, beta 1 Mus musculus