Title : Renal phosphate wasting in the absence of adenylyl cyclase 6.

Pub. Date : 2014 Dec

PMID : 24854272






4 Functional Relationships(s)
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1 Acute activation of the calcium-sensing receptor or feeding a zero phosphate diet almost completely suppressed plasma PTH levels in both AC6(-/-) and WT mice, indicating a secondary cause for hyperparathyroidism. Phosphates adenylate cyclase 6 Mus musculus
2 In conclusion, AC6 in the proximal tubule modulates cAMP formation, Npt2a trafficking, and urinary phosphate excretion, which are highlighted by renal phosphate wasting in AC6(-/-) mice. Cyclic AMP adenylate cyclase 6 Mus musculus
3 In conclusion, AC6 in the proximal tubule modulates cAMP formation, Npt2a trafficking, and urinary phosphate excretion, which are highlighted by renal phosphate wasting in AC6(-/-) mice. Phosphates adenylate cyclase 6 Mus musculus
4 In conclusion, AC6 in the proximal tubule modulates cAMP formation, Npt2a trafficking, and urinary phosphate excretion, which are highlighted by renal phosphate wasting in AC6(-/-) mice. Phosphates adenylate cyclase 6 Mus musculus