Title : Proline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage response.

Pub. Date : 2014 Sep

PMID : 24786831






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PELP1 is phosphorylated at Serine1033 by various DDR kinases like ataxia-telangiectasia mutated, ataxia telangiectasia and Rad3-related or DNAPKc and this phosphorylation of PELP1 is important for p53 coactivation functions. serine1033 proline, glutamate and leucine rich protein 1 Homo sapiens
2 PELP1 is phosphorylated at Serine1033 by various DDR kinases like ataxia-telangiectasia mutated, ataxia telangiectasia and Rad3-related or DNAPKc and this phosphorylation of PELP1 is important for p53 coactivation functions. serine1033 proline, glutamate and leucine rich protein 1 Homo sapiens
3 PELP1-depleted p53 (wild-type) breast cancer cells were less sensitive to various genotoxic agents including etoposide, camptothecin or gamma-radiation. Etoposide proline, glutamate and leucine rich protein 1 Homo sapiens
4 PELP1-depleted p53 (wild-type) breast cancer cells were less sensitive to various genotoxic agents including etoposide, camptothecin or gamma-radiation. Camptothecin proline, glutamate and leucine rich protein 1 Homo sapiens