Title : The suppressive effects of type beta transforming growth factor (TGF beta) on primitive murine hemopoietic progenitors are abrogated by interleukin-6 and granulocyte colony-stimulating factor.

Pub. Date : 1989 Oct

PMID : 2476639






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The suppressive effects of TGF beta were more profound on colony formation from cells of 5-fluorouracil (5-FU)-treated mice than those of normal mice. Fluorouracil transforming growth factor, beta 1 Mus musculus
2 The suppressive effects of TGF beta were more profound on colony formation from cells of 5-fluorouracil (5-FU)-treated mice than those of normal mice. Fluorouracil transforming growth factor, beta 1 Mus musculus
3 Addition of IL-6 or granulocyte colony-stimulating factor (G-CSF), which act synergistically with IL-3 on dormant progenitors, partially neutralized the inhibition by TGF beta of colony formation from cells of 5-FU-treated mice. Fluorouracil transforming growth factor, beta 1 Mus musculus