Title : Inhibition of mTOR signaling reduces PELP1-mediated tumor growth and therapy resistance.

Pub. Date : 2014 Jun

PMID : 24688046






2 Functional Relationships(s)
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Protein Name
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1 mTOR-targeting drugs (rapamycin and AZD8055) significantly reduced proliferation of PELP1-overexpressed breast cancer cells in both in vitro and in vivo xenograft tumor models. Sirolimus proline, glutamate and leucine rich protein 1 Homo sapiens
2 mTOR-targeting drugs (rapamycin and AZD8055) significantly reduced proliferation of PELP1-overexpressed breast cancer cells in both in vitro and in vivo xenograft tumor models. (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol proline, glutamate and leucine rich protein 1 Homo sapiens