Title : Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergistic effects with pyrimidine analogues in lymphoid malignancies.

Pub. Date : 2014

PMID : 24626203






1 Functional Relationships(s)
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1 Furthermore, bendamustine increased the expression of ENT1 at both mRNA and protein levels and enhanced the uptake of Ara-C and subsequent increase in Ara-C triphosphate (Ara-CTP) in HBL-2 cells to an extent comparable with the purine analog fludarabine. Bendamustine Hydrochloride solute carrier family 29 member 1 (Augustine blood group) Homo sapiens