Title : Pharmacological modulation of CRH-stimulated ACTH secretion by ketoconazole.

Pub. Date : 1987

PMID : 2450825






4 Functional Relationships(s)
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1 Pharmacological modulation of CRH-stimulated ACTH secretion by ketoconazole. Ketoconazole corticotropin releasing hormone Rattus norvegicus
2 The effect of CRH to release ACTH was fully restored after KC was removed from the medium. Ketoconazole corticotropin releasing hormone Rattus norvegicus
3 The effects of KC on ACTH release and biosynthesis seems to be mediated by cyclic AMP (cAMP) since KC inhibits basal and CRH stimulated cAMP release and content within the same dose range. Ketoconazole corticotropin releasing hormone Rattus norvegicus
4 The effects of KC on ACTH release and biosynthesis seems to be mediated by cyclic AMP (cAMP) since KC inhibits basal and CRH stimulated cAMP release and content within the same dose range. Ketoconazole corticotropin releasing hormone Rattus norvegicus