Title : Hemorrhagic toxicity of d-alpha-tocopherol in the rat.

Pub. Date : 1990 Aug

PMID : 2399533






1 Functional Relationships(s)
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1 When male Sprague-Dawley rats were administered d-alpha-tocopherol and butylated hydroxytoluene in the diet or intraperitoneally for 7 days, prolongations of prothrombin time and partial thromboplastin time were observed in those given both chemicals by both routes in a dose-dependent manner. alpha-Tocopherol coagulation factor II Rattus norvegicus