Title : Mechanism of action of an inhibitor of complement-mediated prevention of immune precipitation.

Pub. Date : 1990 Jun

PMID : 2373514






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The addition of Fab anti-gp60 to normal serum was associated with (i) increased levels of complement-mediated prevention of immune precipitation (PIP); (ii) increased total haemolytic complement activity when EAIgG, but not when EAIgM, were used as targets; and (iii) increased immune complex-mediated complement activation. pip FA complementation group B Homo sapiens
2 The findings that Fab anti-gp60 (i) only partly restored PIP in RA sera showing reduced PIP levels and (ii) only partly reduced inhibition of PIP by RA sera, show that gp60 is not entirely responsible for these abnormalities. pip FA complementation group B Homo sapiens
3 The findings that Fab anti-gp60 (i) only partly restored PIP in RA sera showing reduced PIP levels and (ii) only partly reduced inhibition of PIP by RA sera, show that gp60 is not entirely responsible for these abnormalities. pip FA complementation group B Homo sapiens
4 The findings that Fab anti-gp60 (i) only partly restored PIP in RA sera showing reduced PIP levels and (ii) only partly reduced inhibition of PIP by RA sera, show that gp60 is not entirely responsible for these abnormalities. pip FA complementation group B Homo sapiens