Title : Poloxamine-cyclodextrin-simvastatin supramolecular systems promote osteoblast differentiation of mesenchymal stem cells.

Pub. Date : 2013 Jun

PMID : 23610048






2 Functional Relationships(s)
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1 Incorporation of 5% alphaCD transforms dilute T908 solutions (as low as 2% copolymer) into gels, enhances the osteoinductive activity of T908, and provides simvastatin sustained release for more than one week, which results in higher and more prolonged alkaline phosphatase (ALP) activity. alpha-cyclodextrin alkaline phosphatase, placental Homo sapiens
2 Incorporation of 5% alphaCD transforms dilute T908 solutions (as low as 2% copolymer) into gels, enhances the osteoinductive activity of T908, and provides simvastatin sustained release for more than one week, which results in higher and more prolonged alkaline phosphatase (ALP) activity. alpha-cyclodextrin alkaline phosphatase, placental Homo sapiens