Title : PELP1 oncogenic functions involve CARM1 regulation.

Pub. Date : 2013 Jul

PMID : 23486015






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Our results show that PELP1 recognizes histones modified by arginine and lysine dimethylation. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens
2 Our results show that PELP1 recognizes histones modified by arginine and lysine dimethylation. Lysine proline, glutamate and leucine rich protein 1 Homo sapiens
3 Chromatin immunoprecipitation assays revealed that PELP1 alters histone H3 arginine methylation status at ERalpha target gene promoters. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens
4 The critical role of PELP1 status in modulating arginine methylation status was also observed through in vivo studies where PELP1 knockdown mediated decreased tumorigenesis correlated with decreased arginine dimethylation. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens
5 The critical role of PELP1 status in modulating arginine methylation status was also observed through in vivo studies where PELP1 knockdown mediated decreased tumorigenesis correlated with decreased arginine dimethylation. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens
6 The critical role of PELP1 status in modulating arginine methylation status was also observed through in vivo studies where PELP1 knockdown mediated decreased tumorigenesis correlated with decreased arginine dimethylation. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens
7 The critical role of PELP1 status in modulating arginine methylation status was also observed through in vivo studies where PELP1 knockdown mediated decreased tumorigenesis correlated with decreased arginine dimethylation. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens
8 Our findings show PELP1 is a reader of histone arginine methyl modifications and deregulation promotes tumor proliferation via epigenetic alterations at ERalpha target promoters. Arginine proline, glutamate and leucine rich protein 1 Homo sapiens