Title : Time course of inhibition of acetylcholinesterase and aliesterases following parathion and paraoxon exposures in rats.

Pub. Date : 1990 May

PMID : 2339415






6 Functional Relationships(s)
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1 Time course of inhibition of acetylcholinesterase and aliesterases following parathion and paraoxon exposures in rats. Parathion acetylcholinesterase Rattus norvegicus
2 Time course of inhibition of acetylcholinesterase and aliesterases following parathion and paraoxon exposures in rats. Paraoxon acetylcholinesterase Rattus norvegicus
3 Acetylcholinesterase is the target enzyme for organophosphate toxicity while aliesterases are alternative targets for organophosphate inhibition which could serve in a protective capacity during organophosphate intoxication. Organophosphates acetylcholinesterase Rattus norvegicus
4 Acetylcholinesterase is the target enzyme for organophosphate toxicity while aliesterases are alternative targets for organophosphate inhibition which could serve in a protective capacity during organophosphate intoxication. Organophosphates acetylcholinesterase Rattus norvegicus
5 Acetylcholinesterase is the target enzyme for organophosphate toxicity while aliesterases are alternative targets for organophosphate inhibition which could serve in a protective capacity during organophosphate intoxication. Organophosphates acetylcholinesterase Rattus norvegicus
6 Pretreatment with phenobarbital slowed the time course of acetylcholinesterase and hepatic aliesterase inhibition following parathion exposure, suggesting the induction of a detoxication pathway(s) to a greater extent than the induction of activation. Phenobarbital acetylcholinesterase Rattus norvegicus